Conveners
Session 4: X-ray Crystallography for Bio-Science (Chair : Sun-Shin Cha)
- Bongjin Mun (Gwangju Institute of Science and Technology)
- Daniele de Sanctis (ESRF-EBS)
- Hyun Kyu Song (Korea University)
Description
This session will introduce life science research through protein structure analysis, followed by a presentation on time-resolved structural studies conducted at ESRF-EBS (France, EU). Recent advancements and ongoing research in ambient-pressure photoelectron spectroscopy will also be discussed.
PROTEOLYSIS1 (PRT1), an N-recognin of Arabidopsis thaliana, has a specificity for recognizing the N-terminal aromatic hydrophobic residue (Tyr/Phe/Trp) of its substrates, subsequently degrading them through ubiquitylation. Here, I represent the complex structures of the ZZ domain of A. thaliana PRT1 (PRT1ZZ) with bulky hydrophobic N-degron peptides. Unlike other ZZ domains, the binding site of...
Serial macromolecular crystallography (SMX) has become a powerful method for resolving
the structures of biological macromolecules at room temperature (RT). Although microfocus
beamlines at third-generation synchrotrons are instrumental, their data acquisition is typically
limited to the millisecond scale due to constraints in photon flux and detector speed. The
newly developed ID29...
